Prof. Christina Yap

Christina Yap is a Professor of Clinical Trials Biostatistics and Group Leader of Early Phase
and Adaptive Trials at The Institute of Cancer Research in London, UK.

Christina is a Statistical Methodologist and Clinical Trialist with over 20 years of experience, serving as the lead statistician for more than 20 trials.  Her expertise includes developing
and implementing efficient designs and analyses, encompassing adaptive designs in early
phase dose-finding trials as well as multi-arm multi-stage Phase II/III trials, with a focus on Bayesian approaches. Her research also focuses on integrating patient-reported outcomes
(PROs) in early phase trials to enhance decision-making and promote patient-centered care, and she leads international initiatives in this area of PRO research.  She is committed to improving the transparency and quality of trial protocols, statistical analysis plans, and trial result publications, contributing to several international consensus-based guidance initiatives, including leading the SPIRIT and CONSORT extensions for dose-finding trials.

Christina actively serves on funding panels, including the Cancer Research UK Clinical
Research Committee. She co-leads the Precision Medicine Working Group within the UK Trials Methodology Research Partnership and the NIHR Statistics Group – Early Phase Trials.